Rapamycin can delay skin aging
As you get older, your skin becomes less elastic and can no longer resist the effects of gravity, sagging and wrinkling. This is an inevitable part of the body's development, and we can only learn to accept it. At the same time, there are options to make the phenomenon come later. In addition to supplements, serums and diet, a new discovery may provide us with new options.
Rapamycin, a drug commonly used to prevent organ rejection after transplants, can also slow the aging of human skin, according to a paper published in Geroscience. Initial studies had suggested the drug could be used to slow aging in mice, flies and worms, but the current study is the first to show that the drug has an effect on aging in human tissues, especially skin, and can reduce the signs of aging.
In the study, 13 participants over the age of 40 were given rapamycin cream once every 1-2 days on each hand and a placebo on the other hand for 8 months. The researchers examined the participants after two, four, six and eight months. After eight months, most of the hand collagen with rapamycin was increased, and the level of p16 protein representing cell senescence was significantly reduced. In addition to cosmetic effects, higher levels of p16 can also lead to atrophy of the skin. Fragile skin tends to tear, wounds heal slowly after an injury, and the risk of infection and other complications increases.
Researchers say that rapamycin can block "targets," which play a signalling role in human cell metabolism, growth, and aging. In addition to its current use to prevent organ rejection, rapamycin is currently prescribed for the treatment of the rare pulmonary disease lymphangioleiomyomatosis. The drug has new applications for extending human life or improving human performance at low doses.
As research on rapamycin has increased in recent years, other miraculous effects have been discovered. We believe that, as long as we keep studying, we will always uncover the mystery.
Our DLdevelop has developed a variety of Elisa products. If you want to know more, you could contact our professional staff directly or directly to our website:
http://www.dldevelop.com
Rapamycin, a drug commonly used to prevent organ rejection after transplants, can also slow the aging of human skin, according to a paper published in Geroscience. Initial studies had suggested the drug could be used to slow aging in mice, flies and worms, but the current study is the first to show that the drug has an effect on aging in human tissues, especially skin, and can reduce the signs of aging.
In the study, 13 participants over the age of 40 were given rapamycin cream once every 1-2 days on each hand and a placebo on the other hand for 8 months. The researchers examined the participants after two, four, six and eight months. After eight months, most of the hand collagen with rapamycin was increased, and the level of p16 protein representing cell senescence was significantly reduced. In addition to cosmetic effects, higher levels of p16 can also lead to atrophy of the skin. Fragile skin tends to tear, wounds heal slowly after an injury, and the risk of infection and other complications increases.
Researchers say that rapamycin can block "targets," which play a signalling role in human cell metabolism, growth, and aging. In addition to its current use to prevent organ rejection, rapamycin is currently prescribed for the treatment of the rare pulmonary disease lymphangioleiomyomatosis. The drug has new applications for extending human life or improving human performance at low doses.
As research on rapamycin has increased in recent years, other miraculous effects have been discovered. We believe that, as long as we keep studying, we will always uncover the mystery.
Our DLdevelop has developed a variety of Elisa products. If you want to know more, you could contact our professional staff directly or directly to our website:
http://www.dldevelop.com
